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What is Stiolto Respimat used for?

Stiolto Respimat inhaler is a maintenance treatment for the symptoms of Chronic obstructive pulmonary disease (COPD). People with COPD experience symptoms include coughing, wheezing and breathing problems including chronic bronchitis and emphysema. These problems can prevent individuals from getting the most out of work, activities and athletics. Spiolto Respimat (tiotropium bromide and olodaterol) has a combination of drugs that work together to relax the muscles of the airways to make breathing easier. This is not used to treat sudden symptoms as it will not provide relief quickly enough to be effective. This is a long term, long acting beta agonist (LABA) maintenance drug. This is not approved to manage asthma as the combination of drugs are not compatible for asthma treatment. There have not been any clinical trials, double blind or controlled trials that verify the safety and efficacy of Spiolto Respimat to treat asthma. Do not share this medication with acquaintances even if they have similar symptoms. It may not help their medical conditions and can result in health complications.
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Stiolto Respimat Inhaler Information

How to use Stiolto Respimat?

Your doctor will inform you how to use this medication, and may even provide a demonstration of the device. The manufacturer's packaging should also come with an illustration that provides a visual reference. If it is difficult to understand and you have additional questions, contact a doctor or pharmacist to ensure you are proficient using this product.

When you first use the respimat you will have to prime the device. To prime the device, load a cartridge and press the release button to discharge an inhalation spray. The device should be pointed away from you to avoid contact with your eyes. Prime a total of four doses prior to use. It also needs to be primed if the device is not used for several days.

Use this medication around the same time every day to get the most benefit from it. Do not stop taking this once you feel better as symptoms can return. If you happen to miss a dose simply skip the missed one and continue your regular schedule. Do not take a double dose to “catch up” as this will not accelerate treatment and may increase the risk of side effects.

What are the side effects of Stiolto Respimat?

  • dizziness
  • nervousness
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  • increase in heart rate
  • pain in the joints
  • dry mouth
  • troubled swallowing
  • pain or tenderness around the eyes and cheekbones
  • blurred vision
  • Chest pain
  • visual halos or colored images
  • decrease in the frequency of urination
  • hoarseness
  • blindness
  • swelling or inflammation of the mouth
  • nausea
  • difficult, burning, or painful urination
  • eye pain or discomfort
  • mouth ulcers
  • trouble breathing
  • fainting
  • frequent urge to urinate
  • pounding in the ears
  • wrinkled skin
  • swelling of the eyelids, face, lips, hands, or feet
  • tearing
  • sore throat
  • joint pain, stiffness, or swelling
  • bleeding gums
  • sneezing
  • rapid breathing
  • creamy white, curd-like patches in the mouth or throat
  • dry skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • vomiting
  • Bladder pain
  • pain when eating or swallowing
  • redness and swelling of the gums
  • tightness in the chest
  • lightheadedness
  • lower back or side pain
  • headache
  • irritation
  • redness of the skin
  • fast or irregular heartbeat
  • cough
  • difficulty with moving
  • heartburn
  • difficulty having a bowel movement
  • unusual tiredness or weakness
  • irritation in the mouth
  • voice changes
  • redness, swelling, or soreness of the tongue
  • thirst
  • trouble sleeping
  • stuffy or runny nose
  • sunken eyes
  • decreased vision
  • slow or fast heartbeat
  • difficulty in passing urine (dribbling)
  • fever
  • bloody nose
  • muscle pain or stiffness
  • chills
  • confusion
  • Back pain
  • bloody or cloudy urine
  • hives, itching, or rash

What are the drug interactions with Stiolto Respimat?

  • Donepezil
  • Trifluoperazine
  • Clomipramine
  • Carbinoxamine
  • Darifenacin
  • Methacholine
  • Chlorpromazine
  • Mepenzolate
  • Promethazine
  • Chlorpheniramine
  • Hydroxyzine
  • Scopolamine
  • Trospium
  • Glycopyrronium Tosylate
  • Aclidinium
  • Paroxetine
  • Procyclidine
  • Loxapine
  • Tropicamide
  • Clemastine
  • Umeclidinium
  • Benztropine
  • Doxepin
  • Amitriptyline
  • Carisoprodol
  • Biperiden
  • Ipratropium
  • Orphenadrine
  • Thiothixene
  • Stramonium
  • Tolterodine
  • Perphenazine
  • Propiverine
  • Trimipramine
  • Solifenacin
  • Olanzapine
  • Hyoscyamine
  • Brompheniramine
  • Dimenhydrinate
  • Flavoxate
  • Imipramine
  • Atropine
  • Oxybutynin
  • Tizanidine
  • Glycopyrrolate
  • Thioridazine
  • Clidinium
  • Pimozide
  • Amifampridine
  • Cyclobenzaprine
  • Revefenacin
  • Terodiline
  • Clozapine
  • Fesoterodine
  • Cyproheptadine
  • Oxitropium Bromide
  • Desipramine
  • Homatropine
  • Amoxapine
  • Cyclopentolate
  • Meclizine
  • Propantheline
  • Belladonna
  • Fluphenazine
  • Pipenzolate Bromide
  • Prochlorperazine
  • Nortriptyline
  • Trihexyphenidyl
  • Protriptyline
  • Diphenhydramine
  • Tiotropium
  • Pirenzepine
  • Dicyclomine

What is the recommended dosage of Spiolto Respimat?

The recommended dose of Spiolto Respimat is 2 puffs once a day, taken at the same time each day. This delivers 5 micrograms of tiotropium and 5 micrograms of olodaterol. It’s important not to take more than the prescribed dose, as it won’t improve effectiveness and may cause side effects. If you have other medical conditions or are using additional medications, your doctor may adjust the dosage. Always follow your doctor’s instructions and consult them if you have any questions.

How much does Spiolto Respimat cost in Canada?

Inspiolto Respimat (known as Spiolto Respimat) cost in Canada

- 60 puffs - $149.53 USD ($2.49 per puffs)
- 120 puffs - $256.56 USD ($2.14 per puffs)
- 180 puffs - $384.65 USD ($2.14 per puffs)

Please scroll up to view the exact pricing for each product, available in different strengths for both brand and generic options.

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Stiolto Respimat Inhaler FAQs

Is Spiolto Respimat a rescue inhaler?

No, Spiolto Respimat is not a rescue inhaler. It is a maintenance medication designed for long-term management of chronic obstructive pulmonary disease (COPD). It helps improve breathing and reduce symptoms over time but is not meant for quick relief of sudden breathing difficulties. If you experience worsening symptoms or frequent breathing difficulties, consult your doctor for proper management.

How long does it take for Spiolto Respimat to start working?

Spiolto Respimat starts working within a few minutes, but it may take a few days to feel the full effects.

How many times a day should I use Spiolto Respimat?

You should use Spiolto Respimat once a day, with two puffs at the same time each day, as directed by your doctor.

How long does Spiolto Respimat last after each dose?

Each dose of Spiolto Respimat provides effects that last for 24 hours, so it's taken once daily. It helps keep your airways open and manage symptoms of COPD or asthma for a full day. Always follow your doctor's instructions on how to use it.

Can Spiolto Respimat be used for asthma?

Spiolto Respimat should not be used to treat asthma. It is specifically designed for the treatment of chronic obstructive pulmonary disease (COPD). Always follow your doctor's recommendations and use the medication as prescribed.

Who should not use Spiolto Respimat?

Spiolto Respimat should not be used by people who are allergic to any of its ingredients. It’s also not safe for those with narrow-angle glaucoma, urinary problems (like an enlarged prostate), or a history of severe allergic reactions. People with heart issues, such as irregular heart rhythms or serious heart disease, should avoid it. It’s not recommended for asthma patients who aren’t also using an inhaled steroid, as it’s not meant for treating asthma attacks. Pregnant or breastfeeding women should only use Stiolto if their doctor says it’s okay. Always talk to your doctor before using Stiolto to make sure it’s right for you.

Disclaimer: The information provided here is intended to provide basic information on this medication and is not intended to replace the medical advice provided by a certified medical professional. Any prescription drug use needs to be approved by your doctor. Do not avoid or ignore any advice provided by your physician in favor of what is written here. Always consult with a pharmacist or doctor before taking this medication and seek counselling if you have any questions or concerns about your medication.

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