What is Xeljanz used for?
Xeljanz is used to treat autoimmune diseases, such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It helps to reduce inflammation, pain, and swelling by affecting the immune system.
Xeljanz (Tofacitinib) Information
How should I take Xeljanz?
When taking Xeljanz, your dose depends on your condition. For rheumatoid arthritis and psoriatic arthritis, you typically start with 5 mg twice a day.
After a while, your doctor may change it to either 5 mg twice a day or 10 mg once a day. For ulcerative colitis, you start with 10 mg twice a day for 8 weeks, then your doctor will adjust it to 5 mg or 10 mg once a day.
For ankylosing spondylitis, you usually start with 5 mg twice a day, and your doctor may change it to 10 mg once a day or 5 mg twice a day.
You can take Xeljanz with or without food, but swallow the tablet whole—don’t crush, break, or chew it.
Try to take it at the same time every day to help remember. If you miss a dose, take it as soon as you remember, unless it’s nearly time for your next dose.
Don’t take two doses at once. Your doctor will monitor you for side effects, so be sure to attend all follow-up appointments.
Let your doctor know if you’re taking other medications or drinking alcohol. Always follow your doctor's instructions, and ask if you have any questions.
What are the common side effects of Xeljanz?
Some known common side effects of Xeljanz include:
- Cough
- Blood in Phlegm
- Urinating More Often Than Normal
- Fever
- Sweating or Chills
- Warm, Red, or Painful Skin or Sores on Your Body
- Muscle Aches
- Shortness of Breath
- Burning When You Urinate
This is not a complete list of side effects and others may occur. Call your doctor for medical advice if you experience any unusual symptoms.
What are the Drug Interactions of Xeljanz?
The list provided below includes drugs that are recognized to interact with Xeljanz. However, it is important to note that this is not an exhaustive compilation of all potential drug interactions.
- Plaquenil (Hydroxychloroquine)
- Methotrexate
- Prednisone
- Meloxicam
- Omeprazole
- Leflunomide
- Hydroxychloroquine
- Tramadol
- Humira (Adalimumab)
To ensure your safety and prevent any adverse interactions, it is crucial to disclose all of your current medications, including prescription medications and OTC products, to your doctor. They will assess the potential interaction and determine whether it is beneficial to use both drugs together or if adjustments need to be made to your treatment plan.
What is the recommended dosage of Xeljanz?
The recommended dosage of Xeljanz (tofacitinib) varies depending on the condition being treated. For rheumatoid arthritis and psoriatic arthritis, the typical dose is 5 mg taken twice a day. For ulcerative colitis, the starting dose is usually 10 mg twice a day for up to 8 weeks, after which the dose may be reduced to 5 mg or 10 mg twice a day based on the response. It is important to follow your doctor's specific instructions for the correct dosage.
How much does Xeljanz cost in Canada?
Starting price of Xeljanz 5mg Tablet in Canada
- 60 tabs - $2426.26 USD ($40.44 per tab)
- 120 tabs - $4809.82 USD ($40.08 per tab)
- 180 tabs - $7210.82 USD ($40.06 per tab)
Scroll up to see the specific pricing for each product, which is available in various strengths for both brand-name and generic options.
How much does Generic Tofacitinib cost in Canada?
Starting price of Tofacitinib 5mg Tablet (generic equivalent to Xeljanz) in Canada
- 60 tabs - $419.99 USD ($7.00 per tab)
- 120 tabs - $819.99 USD ($6.83 per tab)
- 180 tabs - $1197.99 USD ($6.66 per tab)
Scroll up to see the specific pricing for each product, which is available in various strengths for both brand-name and generic options.
Xeljanz (Tofacitinib) FAQs
How long does it take for Xeljanz to start working?
Xeljanz typically starts to show effects within 2 to 4 weeks, but it may take up to 12 weeks to feel its full benefits, depending on the condition being treated.
Can Xeljanz be used in children?
Yes, Xeljanz can be used in children, but it is only approved for certain conditions. For example, it is approved to treat moderate to severe ulcerative colitis in children aged 5 years and older. However, its use in children for other conditions should be determined by a doctor.
Can Xeljanz cause heart problems?
Xeljanz may cause heart problems in some people. It may increase the risk of serious heart issues, such as blood clots, heart attacks, or strokes. People with certain heart conditions should use Xeljanz cautiously and under close medical supervision. It's important to discuss any heart problems with your doctor before starting treatment with Xeljanz.
Can Xeljanz be taken with methotrexate?
Xeljanz can be taken with methotrexate. In fact, it is often prescribed together with methotrexate to treat conditions like rheumatoid arthritis. However, it's important to follow your doctor's advice and regularly monitor for any side effects or complications. Always consult your doctor before combining medications.
How often should I have blood tests while on Xeljanz?
While on Xeljanz, you should have blood tests regularly to monitor your health. Typically, your doctor will recommend testing every 3 months, especially during the first year of treatment. However, the exact frequency may vary based on your individual condition and your doctor's advice. Make sure to follow your healthcare provider's instructions for the best results.
Is Xeljanz safe for people with diabetes?
Xeljanz (tofacitinib) may be used by people with diabetes, but it should be done under the supervision of a doctor. It may affect blood sugar levels, so it's important to monitor them closely while taking the medication. If you have diabetes, talk to your healthcare provider about the potential risks and benefits before starting Xeljanz.
Is there a generic version of Xeljanz available?
Yes, there is a generic version of Xeljanz available. It is called tofacitinib, which is the active ingredient in Xeljanz. The generic version works the same way as the brand-name drug.